Press Release

June 14, 2016 — For Immediate Release

white paperAdvantaPure® Offers a New White Paper Focusing on Molded Tubing Connections
Illustrates the Risks & Expenses of Fluid Leaks in Biopharma and Pharmaceutical Manufacturing Operations; Offers Options

Southampton, PA —AdvantaPure has introduced a white paper that compares the uncertainty of tube sets made with barbed fittings to assemblies manufactured using leak-proof molded connections. Titled "How Molded Manifold Assemblies Prevent Leaks and Costly Consequences," the report describes how leak risks increase with each additional barbed fitting connection in an assembly and offers a solution to reduce that risk.

Moving fluid from point A to point B typically involves a number of tubing-to-fitting connections, along with components such as filters, sampling bags and bottles, all of which require cable ties for secure attachment. When connections leak, the result can involve contamination, production delays and lost income – even into the range of millions of dollars. By incorporating molded tubing connections, the risk of leaks is greatly reduced and the success rate of maintaining sterile pharma and biopharma products is increased.

The white paper explains the challenges involving a sterile fluid flow system, such as flow disruptions, meeting strict governing-association requirements, minimizing cleaning and validation requirements, and maintaining operator safety. It examines how each individual barbed connection in a tube set puts the entire fluid transfer process at risk and how much that risk rises based on the total number of connections in an assembly.

Solutions to the problem are also presented in the paper and include suggestions to replace traditional barbed fittings and cable ties with leak-proof molded connections. These types of connections offer smooth, crevice-free inner surfaces and eliminate cable ties, which can puncture components like bags.

"How Molded Manifold Assemblies Prevent Leaks and Costly Consequences" includes photographs and illustrations for easy visual explanations of the situations described. Other white papers focusing on Single-Use tubing, closures and stopper systems, and clean room fluid transfer options are also available.

For a copy of the white paper, visit or contact the AdvantaPure team at 145 James Way, Southampton, PA 18966; phone 888-755-4370 or 215-526-2151; fax 888-258-4293 or 215-526-2167; e-mail:

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About AdvantaPure and NewAge Industries
AdvantaPure, a division of NewAge Industries, specializes in clean products for the pharmaceutical, biomedical, food, beverage, chemical, and cosmetic industries. All products are manufactured, stored, and shipped using the cleanest methods possible to ensure unsurpassed product purity.

In business since 1954, NewAge Industries is a manufacturer and fabricator of thermoplastic and thermoset tubing and hose, and a supplier of fittings and clamps. The company offers one of the broadest product lines of tubing, hose, and fittings in the U.S., and its custom extrusion and fabrication services are unrivaled. In 2006, NewAge Industries initiated an ESOP (Employee Stock Ownership Plan) for the benefit of both its employees and customers.