Phone: 1-888-755-4370 (toll free US only) Phone: 1-215-526-2151 (worldwide) Email: info@www.advantapure.com
BioClosure® Cap Assemblies for AdvantaPure Carboys
Available in five carboy cap capacities from 2.5 to 40 liter- 2-port and 3-port closure configurations
- Fit carboys with 80mm and 120mm neck size
- Can be sterilized via gamma irradiation or autoclave
- AdvantaFlex® tubing with plugged end and fill line to bottom of carboy for easy transfer
- 0.2 um filter for sterile gas venting
- BioClosure assemblies for 20 liter and 40 liter carboys include an adapter cone
- Custom lengths and configurations available upon request
- Also available in platinum cured silicone
APPLICATIONS
- Media/Buffer Storage
- Sterile Filling
- Vaccine Production
- Process R&D
SPECIFICATIONS
for 2-Port BioClosure Cap Assemblies for AdvantaPure Carboys, Molded Style
| Product Number | Carboy Capacity |
| AFCA2-83-0250 | 2.5 Liter |
| AFCA2-83-0500 | 5 Liter |
| AFCA2-83-1000 | 10 Liter |
| AFCA2-83-2000 | 20 Liter |
| AFCA2-83-4000 | 40 Liter |
| Note: 2-Port BioClosure Cap Assembles are supplied non-sterile. | |
All 2-port, molded AdvantaFlex BioClosure Cap Assemblies are supplied with one (1) 1/4″ I.D. x 1/2″ O.D. AdvantaFlex vent line and one (1) 1/4″ I.D. x 1/2″ O.D. AdvantaFlex fill line.
SPECIFICATIONS
for 3-Port BioClosure Cap Assemblies for AdvantaPure Carboys, 1/4″ Hose Barb Adapter Style
| Product Number | Carboy Capacity |
| AFCA3-83x-0250-04 | 2.5 Liter |
| AFCA3-83x-0500-04 | 5 Liter |
| AFCA3-83x-1000-04 | 10 Liter |
| AFCA3-83x-2000-04 | 20 Liter |
| AFCA3-83x-4000-04 | 40 Liter |
| Specify gamma sterilized, if required, when ordering. Examples: A non-sterile, 10 Liter, 3-Port Cap Assembly is part number AFCA3-83-1000-04. A gamma sterilized, 10 Liter, 3-Port Cap Assembly is part number AFCA3-83GS-1000-04. | |
These 3-port BioClosure Cap Assemblies are supplied with one (1) 1/4″ I.D. x 1/2″ O.D. AdvantaFlex vent line and two (2) 1/4″ I.D. x 1/2″ O.D. AdvantaFlex fill lines.
SPECIFICATIONS
for 3-Port BioClosure Cap Assemblies for AdvantaPure Carboys, 1/2″ Hose Barb Adapter Style
| Product Number | Carboy Capacity |
| AFCA3-83x-0250-08 | 2.5 Liter |
| AFCA3-83x-0500-08 | 5 Liter |
| AFCA3-83x-1000-08 | 10 Liter |
| AFCA3-83x-2000-08 | 20 Liter |
| AFCA3-83x-4000-08 | 40 Liter |
| Specify gamma sterilized, if required, when ordering. Examples: A non-sterile, 10 Liter, 3-Port Cap Assembly is part number AFCA3-83-1000-08. A gamma sterilized, 10 Liter, 3-Port Cap Assembly is part number AFCA3-83GS-1000-08. | |
These 3-port BioClosure Cap Assemblies are supplied with one (1) 1/4″ I.D. x 1/2″ O.D. AdvantaFlex vent line and two (2) 1/2″ I.D. x 3/4″ O.D. AdvantaFlex fill lines.
AdvantaPure Carboys
AdvantaPure Carboys are the ideal choice for advanced fluid handling and have been designed with the end-user in mind. The ergonomically designed body and handles allow the user to easily hold and manipulate the container during lifting, filling and pouring while the novel shape maximizes bench and shelf space. The user-friendly cap has molded finger grips allowing for easy cap removal and attachment while wearing gloves.
Carboys are available with or without spigots and have large levers that control two flow rates – one for continuous, locked flow and the other for faster, manual flow. The spout features 5/8″ and 3/4″ hose barbs and a standard internal luer tape to fit a male barb adapter.
Additional options provide flexibility in drainage, pump connection and automated equipment. Spigot fittings are available as 1/4″, 3/8″, 1/2″ and 3/4″ hose barb adapters, as well as a 3/4″ sanitary Tri-Clamp connector.
Carboy container materials include:
Polypropylene (PP):
- Meets USP Class VI and FDA requirements
- Autoclavable (recommended cycle is 15 PSI for 20 minutes at 121°C)
- Easy to clean and good chemical compatibility to acids and bases
- Temperature range: -40°C to 121°C
- Good for media and buffer solutions
- Top molded handles; available with or without spigot
- Easy to read graduation marks certified to +/- 5% accuracy
Dark Amber Polypropylene (DP):
- Meets USP Class VI and FDA requirements
- Autoclavable (recommended cycle is 15 PSI for 20 minutes at 121°C)
- Easy to clean and good chemical compatibility to acids and bases
- Temperature range -40°C to 121°C
- Amber color helps protect from UV and light that can alter contents in carboy
- Top molded handles; available with or without spigot
- Easy to read graduation marks certified to +/- 5% accuracy
PETG (PG):
- Meets USP Class VI and FDA requirements
- Can be gamma irradiated
- Easy to clean and good chemical compatibility to acids and bases
- Temperature range -40°C to 80°C
- Clear
- Good for media and buffer solutions
- Available with or without spigot
- Easy to read graduation marks certified to +/- 5% accuracy
HDPE:
- Meets USP Class VI and FDA requirements
- Highly chemical resistant to acids and bases
- Temperature range -50°C to 121°C
- Good for buffers and reagents
- Top molded handles; available with or without spigot
- Easy to read graduation marks certified to +/- 5% accuracy
Amber HDPE:
- Meets USP Class VI and FDA requirements
- Highly chemical resistant to acids and bases
- Temperature range -50°C to 121°C
- Excellent for storage of light sensitive materials
- Top molded handles; available with or without spigot
- Easy to read graduation marks certified to +/- 5% accuracy
Carboy capacities range from 2.5 Liter through 40 Liter; not all materials are available in all sizes. Please contact your AdvantaPure Technical Sales Representative at 888-755-4370 (in the U.S.) or 215-526-2151 for more details.
Download a printable version of our BioClosure System Assemblies brochure. BioClosure_System_Assemblies.pdf (685kb)
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Back to BioClosure System Assemblies
for Bottles, Flasks and Carboys
Select from 2-port, molded AdvantaFlex cap assemblies (above)…
…or 3-port, hose barb adapter styles (above)
SINGLE-USE PROCESS MOLDED MANIFOLDS
Eliminate production stoppages for sterilization, reduce the risk of leaks and contamination, and increase efficiency by incorporating Single-Use manifolds from AdvantaPure. Single Use products simplify cleaning validations—use once and discard.
Each manifold is custom made using platinum-cured, Class VI silicone tubing or AdvantaFlex® TPE tubing, molded fittings, BioClosures, filters, bottles, labels and tracking options, and other components.
Contact an AdvantaPure representative today to discuss your application.
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