Phone: 1-888-755-4370 (toll free US only)
Phone: 1-215-526-2151 (worldwide) Email: info@www.advantapure.comAdvantaSil® APHP is a platinum-cured silicone specifically engineered to meet critical pharmaceutical and biopharmaceutical high-pressure applications. Designed for high-volume fluid transfer, APHP stands out as the preferred material due to its higher durometer, providing superior pressure ratings compared to standard unreinforced tubing.
KEY FEATURES
-
- Translucent for fluid flow visibility while withstanding higher pressure
- 80A durometer for high pressure applications
- Higher durometer allows for greater pressure ratings than standard unreinforced tubing
- General temperature range -65°F (-53.9°C) to 400°F (204.4°C)
- Custom lengths, sizes and packaging available
- Manufactured with a focus on sustainability
- Excellent for applications that require processing at higher flow rates
- Produced, assembled and packaged in an ISO Class 7 cleanroom
- Sterilized by autoclave and via gamma irradiation
- Security of supply chain with redundant manufacturing sites
- Wide range of sizes from 0.125" to 1.5" (3.18 mm to 38.1 mm) ID
- Comprehensive validation package available upon request to expedite qualification and validation, including full extractables report (BPOG)
- Now available as mini and standard Tri-Clamp® ends — call for details!
Full BPOG standardized extractables test results available on request
ATTENTION:
Specific cutting techniques are strongly recommended for AdvantaSil APHP High Pressure Silicone Tubing. APHP must be cut with a chevron style cutter at a 90 degree angle to the tubing, leaving a smooth, non-jagged, perpendicular cut at the tubing end. View cutter product details and purchase information at https://www.lislecorp.com/specialty-tools/hose/hose-cutter. See our cutting technique video below.
SPECIFICATIONS
APHP - HIGH PRESSURE SILICONE TUBING

Dimensional Specifications
Product Number | Nominal I.D. | Wall | O.D. | Bend Radius | Standard Available Lengths | ||||
(in.) | (mm) | (in.) | (mm) | (in.) | (mm) | (in.) | (mm) | (ft.) | |
APHP-0125-0250 | .125 | 3.18 | .063 | 1.60 | .250 | 6.35 | .375 | 9.5 | 50 |
APHP-0250-0375 | .250 | 6.35 | .063 | 1.60 | .375 | 9.52 | 1 | 25 | 50 |
APHP-0375-0625 | .375 | 9.52 | .125 | 3.18 | .625 | 15.88 | 1.2 | 30 | 50 |
APHP-0500-0750 | .500 | 12.70 | .125 | 3.18 | .750 | 19.05 | 1.8 | 46 | 50 |
APHP-0750-1000 | .750 | 19.05 | .125 | 3.18 | 1.000 | 25.40 | 2.1 | 53 | 50 |
APHP-1000-1375 | 1.000 | 25.40 | .188 | 4.76 | 1.375 | 34.93 | 4.1 | 104 | 50 |
APHP-1500-1875 | 1.500 | 38.1 | .188 | 4.76 | 1.875 | 47.6 | 6 | 152 | 10 |
Performance Specifications
Product Number | Burst Pressure Non-Treated | Recommended
Working Pressure
based on 3:1
safety factor
Non-Treated
|
Burst Pressure Gamma Irradiated 45kGy |
Recommended
Working Pressure
based on 3:1
safety factor
Gamma Irradiated
45kGy |
Vacuum Capability | ||||
(psi) | (bar) | (psi) | (bar) | (psi) | (bar) | (psi) | (bar) | (in./Hg) | |
APHP-0125-0250 | 175 | 12.1 | 58 | 4.0 | 184 | 12.7 | 61 | 12.7 | >29.5 |
APHP-0250-0375 | 109 | 7.5 | 36 | 2.5 | 127 | 8.8 | 42 | 2.9 | >29.5 |
APHP-0375-0625 | 168 | 11.6 | 56 | 3.9 | 182 | 12.5 | 61 | 4.2 | >29.5 |
APHP-0500-0750 | 124 | 8.5 | 41 | 2.8 | 138 | 9.5 | 46 | 3.2 | >29.5 |
APHP-0750-1000 | 103 | 7.1 | 34 | 2.3 | 113 | 7.8 | 38 | 2.6 | >29.5 |
APHP-1000-1375 | 76 | 5.2 | 25 | 1.7 | 105 | 7.2 | 35 | 2.4 | >29.5 |
APHP-1500-1875 | 83 | 5.7 | 27 | 1.9 | 91 | 6.3 | 30 | 2.1 | >29.5 |
Sold by standard coil length of 50 ft. Add length suffix code "L" to product number when ordering. Example: 50 ft. of .250 in. I.D. x .375 in. O.D. tubing is product number APHP-0250-0375L. Non-listed sizes and custom lengths available by special order. Coils are supplied double bagged in heat-sealed polybags and bulk packed. Contact your AdvantaPure Sales Representative regarding any special product or packaging needs. Recommended working pressures are calculated from burst testing using a 3:1 safety factor. Testing was performed at ambient temperature. Application testing is recommended. CF = Consult factory The 1.5” APHP is compatible with Abec Bioreactors , CPC Aspectic Connectors , and T and Y Connectors from Nordson NOTE: The data listed throughout this web site is meant only as a guide to aid in design, and is believed to be reliable; however, nothing stated shall constitute a guarantee or warranty for any application. Product field-testing should be performed to find the actual values for a specific application. |
APHP CASE STUDY AVAILABLE
This case study describes the performance of AdvantaSil High Pressure Unreinforced Silicone Tubing (APHP) used in a Monoclonal Antibody process for the transfer of buffers in purification.
Download a printable version of our High Pressure Tubing brochure. AdvantaSil_High_Pressure_Tubing.pdf (163kb)

APHP CASE STUDY AVAILABLE
This case study describes the performance of AdvantaSil High Pressure Unreinforced Silicone Tubing (APHP) used in a Monoclonal Antibody process for the transfer of buffers in purification.
SINGLE-USE SYSTEMS
Single-use Systems are custom made using AdvantaSil® platinum-cured, Class VI silicone tubing and hose or AdvantaFlex® Class VI biopharmaceutical grade tubing. Add fittings, stoppers and container closures, filters, bottles, labels and tracking options, and other components.